K286-3862 Screening compound: 5-{[(5-acetyl-2-methoxyphenyl)methyl]sulfanyl}-3-(3-methoxyphenyl)-6-(4-methylphenyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

K286-3862 Screening compound: 5-{[(5-acetyl-2-methoxyphenyl)methyl]sulfanyl}-3-(3-methoxyphenyl)-6-(4-methylphenyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one
K286-3862 Screening compound: 5-{[(5-acetyl-2-methoxyphenyl)methyl]sulfanyl}-3-(3-methoxyphenyl)-6-(4-methylphenyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-3862
5-{[(5-acetyl-2-methoxyphenyl)methyl]sulfanyl}-3-(3-methoxyphenyl)-6-(4-methylphenyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-3862

Molecular Formula

C29H25N3O4S3 (C29 H25 N3 O4 S3)

Compound Name

5-{[(5-acetyl-2-methoxyphenyl)methyl]sulfanyl}-3-(3-methoxyphenyl)-6-(4-methylphenyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

IUPAC name

5-{[(5-acetyl-2-methoxyphenyl)methyl]sulfanyl}-3-(3-methoxyphenyl)-6-(4-methylphenyl)-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-7-one

SMILES

CC(c(cc1)cc(CSC(N(c2ccc(C)cc2)C2=O)=NC(N3c4cc(OC)ccc4)=C2SC3=S)c1OC)=O

InChI

InChI=1S/C29H25N3O4S3/c1-17-8-11-21(12-9-17)32-27(34)25-26(31(29(37)39-25)22-6-5-7-23(15-22)35-3)30-28(32)38-16-20-14-19(18(2)33)10-13-24(20)36-4/h5-15H,16H2,1-4H3

InChI Key

FIBREFMNOXMAKX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15090779

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

575.73

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.777

Distribution Coefficient, logD

5.777

Water Solubility, LogSw

-5.48

Polar Surface Area

55.955

Acid Dissociation Constant (pKa)

21.69

Base Dissociation Constant (pKb)

-9.50

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.20

K286-3862 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-3862 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-3862?
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What is the minimum amount of K286-3862 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-3862
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-3862
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-3862 available by request