K286-3920 Screening compound: N-(3-chloro-4-methylphenyl)-2-{[3-(4-ethylphenyl)-6-(4-fluorophenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide

K286-3920 Screening compound: N-(3-chloro-4-methylphenyl)-2-{[3-(4-ethylphenyl)-6-(4-fluorophenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide
K286-3920 Screening compound: N-(3-chloro-4-methylphenyl)-2-{[3-(4-ethylphenyl)-6-(4-fluorophenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-3920
N-(3-chloro-4-methylphenyl)-2-{[3-(4-ethylphenyl)-6-(4-fluorophenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-3920

Molecular Formula

C28H22ClFN4O2S3 (C28 H22 ClFN4 O2 S3)

Compound Name

N-(3-chloro-4-methylphenyl)-2-{[3-(4-ethylphenyl)-6-(4-fluorophenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide

IUPAC name

N-(3-chloro-4-methylphenyl)-2-{[3-(4-ethylphenyl)-6-(4-fluorophenyl)-7-oxo-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-5-yl]sulfanyl}acetamide

SMILES

CCc(cc1)ccc1N(C(N=C(N(c(cc1)ccc1F)C1=O)SCC(Nc2cc(Cl)c(C)cc2)=O)=C1S1)C1=S

InChI

InChI=1S/C28H22ClFN4O2S3/c1-3-17-5-10-20(11-6-17)33-25-24(39-28(33)37)26(36)34(21-12-7-18(30)8-13-21)27(32-25)38-15-23(35)31-19-9-4-16(2)22(29)14-19/h4-14H,3,15H2,1-2H3,(H,31,35)

InChI Key

YETUDVGPPALBOV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15090818

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

597.16

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

7.258

Distribution Coefficient, logD

7.257

Water Solubility, LogSw

-6.48

Polar Surface Area

50.104

Acid Dissociation Constant (pKa)

11.11

Base Dissociation Constant (pKb)

-9.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

K286-3920 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-3920 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-3920?
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What is the minimum amount of K286-3920 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-3920
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-3920
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-3920 available by request