K286-3942 Screening compound: 3-(2-ethoxyphenyl)-6-(4-fluorophenyl)-5-{[(2-methylphenyl)methyl]sulfanyl}-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

K286-3942 Screening compound: 3-(2-ethoxyphenyl)-6-(4-fluorophenyl)-5-{[(2-methylphenyl)methyl]sulfanyl}-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one
K286-3942 Screening compound: 3-(2-ethoxyphenyl)-6-(4-fluorophenyl)-5-{[(2-methylphenyl)methyl]sulfanyl}-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-3942
3-(2-ethoxyphenyl)-6-(4-fluorophenyl)-5-{[(2-methylphenyl)methyl]sulfanyl}-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-3942

Molecular Formula

C27H22FN3O2S3 (C27 H22 FN3 O2 S3)

Compound Name

3-(2-ethoxyphenyl)-6-(4-fluorophenyl)-5-{[(2-methylphenyl)methyl]sulfanyl}-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

IUPAC name

3-(2-ethoxyphenyl)-6-(4-fluorophenyl)-5-{[(2-methylphenyl)methyl]sulfanyl}-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-7-one

SMILES

CCOc(cccc1)c1N(C(N=C(N(c(cc1)ccc1F)C1=O)SCc2c(C)cccc2)=C1S1)C1=S

InChI

InChI=1S/C27H22FN3O2S3/c1-3-33-22-11-7-6-10-21(22)31-24-23(36-27(31)34)25(32)30(20-14-12-19(28)13-15-20)26(29-24)35-16-18-9-5-4-8-17(18)2/h4-15H,3,16H2,1-2H3

InChI Key

OYRLZQVWUOYCDM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15090835

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

535.69

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.661

Distribution Coefficient, logD

6.661

Water Solubility, LogSw

-5.71

Polar Surface Area

33.864

Acid Dissociation Constant (pKa)

28.43

Base Dissociation Constant (pKb)

1.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.80

K286-3942 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-3942 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-3942?
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What is the minimum amount of K286-3942 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-3942
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-3942
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-3942 available by request