K286-3973 Screening compound: 5-{[(2-chlorophenyl)methyl]sulfanyl}-3-(4-ethoxyphenyl)-6-(4-methylphenyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

K286-3973 Screening compound: 5-{[(2-chlorophenyl)methyl]sulfanyl}-3-(4-ethoxyphenyl)-6-(4-methylphenyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one
K286-3973 Screening compound: 5-{[(2-chlorophenyl)methyl]sulfanyl}-3-(4-ethoxyphenyl)-6-(4-methylphenyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-3973
5-{[(2-chlorophenyl)methyl]sulfanyl}-3-(4-ethoxyphenyl)-6-(4-methylphenyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-3973

Molecular Formula

C27H22ClN3O2S3 (C27 H22 ClN3 O2 S3)

Compound Name

5-{[(2-chlorophenyl)methyl]sulfanyl}-3-(4-ethoxyphenyl)-6-(4-methylphenyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

IUPAC name

5-{[(2-chlorophenyl)methyl]sulfanyl}-3-(4-ethoxyphenyl)-6-(4-methylphenyl)-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-7-one

SMILES

CCOc(cc1)ccc1N(C(N=C(N(c1ccc(C)cc1)C1=O)SCc(cccc2)c2Cl)=C1S1)C1=S

InChI

InChI=1S/C27H22ClN3O2S3/c1-3-33-21-14-12-19(13-15-21)30-24-23(36-27(30)34)25(32)31(20-10-8-17(2)9-11-20)26(29-24)35-16-18-6-4-5-7-22(18)28/h4-15H,3,16H2,1-2H3

InChI Key

OGEOLAGSCYQJGP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15090861

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

552.14

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.961

Distribution Coefficient, logD

6.961

Water Solubility, LogSw

-6.26

Polar Surface Area

34.078

Acid Dissociation Constant (pKa)

28.80

Base Dissociation Constant (pKb)

-7.82

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.80

K286-3973 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-3973 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-3973?
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What is the minimum amount of K286-3973 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-3973
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-3973
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-3973 available by request