K286-4018 Screening compound: 2-{[3-(4-ethylphenyl)-6-(4-methylphenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}-N-(5-methyl-1,2-oxazol-3-yl)acetamide

K286-4018 Screening compound: 2-{[3-(4-ethylphenyl)-6-(4-methylphenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}-N-(5-methyl-1,2-oxazol-3-yl)acetamide
K286-4018 Screening compound: 2-{[3-(4-ethylphenyl)-6-(4-methylphenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}-N-(5-methyl-1,2-oxazol-3-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-4018
2-{[3-(4-ethylphenyl)-6-(4-methylphenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}-N-(5-methyl-1,2-oxazol-3-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-4018

Molecular Formula

C26H23N5O3S3 (C26 H23 N5 O3 S3)

Compound Name

2-{[3-(4-ethylphenyl)-6-(4-methylphenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}-N-(5-methyl-1,2-oxazol-3-yl)acetamide

IUPAC name

2-{[3-(4-ethylphenyl)-6-(4-methylphenyl)-7-oxo-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-5-yl]sulfanyl}-N-(5-methyl-12-oxazol-3-yl)acetamide

SMILES

CCc(cc1)ccc1N(C(N=C(N(c1ccc(C)cc1)C1=O)SCC(Nc2noc(C)c2)=O)=C1S1)C1=S

InChI

InChI=1S/C26H23N5O3S3/c1-4-17-7-11-18(12-8-17)30-23-22(37-26(30)35)24(33)31(19-9-5-15(2)6-10-19)25(28-23)36-14-21(32)27-20-13-16(3)34-29-20/h5-13H,4,14H2,1-3H3,(H,27,29,32)

InChI Key

SZFIJHOKYVAQEF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15090898

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

549.7

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.636

Distribution Coefficient, logD

5.627

Water Solubility, LogSw

-5.30

Polar Surface Area

71.899

Acid Dissociation Constant (pKa)

9.07

Base Dissociation Constant (pKb)

-9.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.20

K286-4018 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-4018 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-4018?
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What is the minimum amount of K286-4018 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-4018
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-4018
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-4018 available by request