K286-4130 Screening compound: 2-fluorophenyl 2-{[3-(4-ethoxyphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetate

K286-4130 Screening compound: 2-fluorophenyl 2-{[3-(4-ethoxyphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetate
K286-4130 Screening compound: 2-fluorophenyl 2-{[3-(4-ethoxyphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-4130
2-fluorophenyl 2-{[3-(4-ethoxyphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-4130

Molecular Formula

C27H20FN3O4S3 (C27 H20 FN3 O4 S3)

Compound Name

2-fluorophenyl 2-{[3-(4-ethoxyphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetate

IUPAC name

2-fluorophenyl 2-{[3-(4-ethoxyphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-5-yl]sulfanyl}acetate

SMILES

CCOc(cc1)ccc1N(C(N=C(N(c1ccccc1)C1=O)SCC(Oc(cccc2)c2F)=O)=C1S1)C1=S

InChI

InChI=1S/C27H20FN3O4S3/c1-2-34-19-14-12-18(13-15-19)30-24-23(38-27(30)36)25(33)31(17-8-4-3-5-9-17)26(29-24)37-16-22(32)35-21-11-7-6-10-20(21)28/h3-15H,2,16H2,1H3

InChI Key

RNWSESWVEOACIP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15090976

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

565.67

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.405

Distribution Coefficient, logD

5.405

Water Solubility, LogSw

-5.38

Polar Surface Area

54.219

Acid Dissociation Constant (pKa)

28.01

Base Dissociation Constant (pKb)

-2.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

K286-4130 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-4130 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-4130?
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What is the minimum amount of K286-4130 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-4130
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-4130
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-4130 available by request