K286-4174 Screening compound: N-cyclopentyl-2-{[3-(3,4-dimethylphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide

K286-4174 Screening compound: N-cyclopentyl-2-{[3-(3,4-dimethylphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide
K286-4174 Screening compound: N-cyclopentyl-2-{[3-(3,4-dimethylphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-4174
N-cyclopentyl-2-{[3-(3,4-dimethylphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-4174

Molecular Formula

C26H26N4O2S3 (C26 H26 N4 O2 S3)

Compound Name

N-cyclopentyl-2-{[3-(3,4-dimethylphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide

IUPAC name

N-cyclopentyl-2-{[3-(34-dimethylphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-5-yl]sulfanyl}acetamide

SMILES

Cc(cc1)c(C)cc1N(C(N=C(N(c1ccccc1)C1=O)SCC(NC2CCCC2)=O)=C1S1)C1=S

InChI

InChI=1S/C26H26N4O2S3/c1-16-12-13-20(14-17(16)2)29-23-22(35-26(29)33)24(32)30(19-10-4-3-5-11-19)25(28-23)34-15-21(31)27-18-8-6-7-9-18/h3-5,10-14,18H,6-9,15H2,1-2H3,(H,27,31)

InChI Key

AVFDVFXJMFDMPB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15091016

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

522.72

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.359

Distribution Coefficient, logD

5.359

Water Solubility, LogSw

-5.19

Polar Surface Area

51.517

Acid Dissociation Constant (pKa)

16.73

Base Dissociation Constant (pKb)

1.81

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.80

K286-4174 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-4174 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-4174?
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What is the minimum amount of K286-4174 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-4174
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-4174
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-4174 available by request