K286-4306 Screening compound: 5-{[(3-fluorophenyl)methyl]sulfanyl}-3-[(furan-2-yl)methyl]-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

K286-4306 Screening compound: 5-{[(3-fluorophenyl)methyl]sulfanyl}-3-[(furan-2-yl)methyl]-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one
K286-4306 Screening compound: 5-{[(3-fluorophenyl)methyl]sulfanyl}-3-[(furan-2-yl)methyl]-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-4306
5-{[(3-fluorophenyl)methyl]sulfanyl}-3-[(furan-2-yl)methyl]-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-4306

Molecular Formula

C23H16FN3O2S3 (C23 H16 FN3 O2 S3)

Compound Name

5-{[(3-fluorophenyl)methyl]sulfanyl}-3-[(furan-2-yl)methyl]-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

IUPAC name

5-{[(3-fluorophenyl)methyl]sulfanyl}-3-[(furan-2-yl)methyl]-6-phenyl-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-7-one

SMILES

O=C1N(c2ccccc2)C(SCc2cc(F)ccc2)=NC(N2Cc3ccco3)=C1SC2=S

InChI

InChI=1S/C23H16FN3O2S3/c24-16-7-4-6-15(12-16)14-31-22-25-20-19(21(28)27(22)17-8-2-1-3-9-17)32-23(30)26(20)13-18-10-5-11-29-18/h1-12H,13-14H2

InChI Key

AUOGXQVRXSRNBB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15091099

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

481.6

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.239

Distribution Coefficient, logD

5.239

Water Solubility, LogSw

-5.35

Polar Surface Area

35.315

Acid Dissociation Constant (pKa)

33.99

Base Dissociation Constant (pKb)

1.54

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.70

K286-4306 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-4306 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-4306?
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What is the minimum amount of K286-4306 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-4306
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-4306
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-4306 available by request