K286-4308 Screening compound: 2-({3-[(furan-2-yl)methyl]-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl}sulfanyl)-N-(1,3-thiazol-2-yl)acetamide

K286-4308 Screening compound: 2-({3-[(furan-2-yl)methyl]-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl}sulfanyl)-N-(1,3-thiazol-2-yl)acetamide
K286-4308 Screening compound: 2-({3-[(furan-2-yl)methyl]-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl}sulfanyl)-N-(1,3-thiazol-2-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-4308
2-({3-[(furan-2-yl)methyl]-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl}sulfanyl)-N-(1,3-thiazol-2-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-4308

Molecular Formula

C21H15N5O3S4 (C21 H15 N5 O3 S4)

Compound Name

2-({3-[(furan-2-yl)methyl]-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl}sulfanyl)-N-(1,3-thiazol-2-yl)acetamide

IUPAC name

2-({3-[(furan-2-yl)methyl]-7-oxo-6-phenyl-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-5-yl}sulfanyl)-N-(13-thiazol-2-yl)acetamide

SMILES

O=C(CSC(N(c1ccccc1)C1=O)=NC(N2Cc3ccco3)=C1SC2=S)Nc1nccs1

InChI

InChI=1S/C21H15N5O3S4/c27-15(23-19-22-8-10-31-19)12-32-20-24-17-16(18(28)26(20)13-5-2-1-3-6-13)33-21(30)25(17)11-14-7-4-9-29-14/h1-10H,11-12H2,(H,22,23,27)

InChI Key

CANHBMUMUYHODJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15091101

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

513.65

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.681

Distribution Coefficient, logD

3.681

Water Solubility, LogSw

-4.05

Polar Surface Area

68.943

Acid Dissociation Constant (pKa)

10.64

Base Dissociation Constant (pKb)

0.50

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.50

K286-4308 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-4308 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-4308?
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What is the minimum amount of K286-4308 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-4308
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-4308
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-4308 available by request