K289-0278 Screening compound: 3-{[7-(4-carbamoylpiperidine-1-carbonyl)-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl]sulfanyl}propanoic acid

K289-0278 Screening compound: 3-{[7-(4-carbamoylpiperidine-1-carbonyl)-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl]sulfanyl}propanoic acid
K289-0278 Screening compound: 3-{[7-(4-carbamoylpiperidine-1-carbonyl)-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl]sulfanyl}propanoic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound K289-0278
3-{[7-(4-carbamoylpiperidine-1-carbonyl)-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl]sulfanyl}propanoic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K289-0278

Molecular Formula

C24H24N4O5S (C24 H24 N4 O5 S)

Compound Name

3-{[7-(4-carbamoylpiperidine-1-carbonyl)-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl]sulfanyl}propanoic acid

IUPAC name

3-{[7-(4-carbamoylpiperidine-1-carbonyl)-4-oxo-3-phenyl-34-dihydroquinazolin-2-yl]sulfanyl}propanoic acid

SMILES

NC(C(CC1)CCN1C(c(cc1)cc(N=C(N2c3ccccc3)SCCC(O)=O)c1C2=O)=O)=O

InChI

InChI=1S/C24H24N4O5S/c25-21(31)15-8-11-27(12-9-15)22(32)16-6-7-18-19(14-16)26-24(34-13-10-20(29)30)28(23(18)33)17-4-2-1-3-5-17/h1-7,14-15H,8-13H2,(H2,25,31)(H,29,30)

InChI Key

JIMAFUQSNKRRGQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15091340

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

480.54

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.419

Distribution Coefficient, logD

-2.277

Water Solubility, LogSw

-2.31

Polar Surface Area

104.522

Acid Dissociation Constant (pKa)

4.71

Base Dissociation Constant (pKb)

2.99

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

K289-0278 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K289-0278 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K289-0278?
Check Price and Availability of K289-0278, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K289-0278 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K289-0278
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K289-0278
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K289-0278 available by request