K290-0046 Screening compound: 8-methoxy-3-(7-phenoxyimidazo[2,1-b][1,3]benzothiazol-2-yl)-2H-chromen-2-one

K290-0046 Screening compound: 8-methoxy-3-(7-phenoxyimidazo[2,1-b][1,3]benzothiazol-2-yl)-2H-chromen-2-one
K290-0046 Screening compound: 8-methoxy-3-(7-phenoxyimidazo[2,1-b][1,3]benzothiazol-2-yl)-2H-chromen-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K290-0046
8-methoxy-3-(7-phenoxyimidazo[2,1-b][1,3]benzothiazol-2-yl)-2H-chromen-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K290-0046

Molecular Formula

C25H16N2O4S (C25 H16 N2 O4 S)

Compound Name

8-methoxy-3-(7-phenoxyimidazo[2,1-b][1,3]benzothiazol-2-yl)-2H-chromen-2-one

IUPAC name

8-methoxy-3-{10-phenoxy-7-thia-25-diazatricyclo[6.4.0.0^{26}]dodeca-1(8)35911-pentaen-4-yl}-2H-chromen-2-one

SMILES

COc1cccc(C=C2c3cn(c(ccc(Oc4ccccc4)c4)c4s4)c4n3)c1OC2=O

InChI

InChI=1S/C25H16N2O4S/c1-29-21-9-5-6-15-12-18(24(28)31-23(15)21)19-14-27-20-11-10-17(13-22(20)32-25(27)26-19)30-16-7-3-2-4-8-16/h2-14H,1H3

InChI Key

KLBFOCMOXPHAKG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15091363

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

440.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.559

Distribution Coefficient, logD

5.559

Water Solubility, LogSw

-5.43

Polar Surface Area

43.929

Acid Dissociation Constant (pKa)

33.29

Base Dissociation Constant (pKb)

1.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.00

K290-0046 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Antimitotic Tubulin Library (17355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with K290-0046 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K290-0046?
Check Price and Availability of K290-0046, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K290-0046 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K290-0046
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K290-0046
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K290-0046 available by request