K292-1343 Screening compound: N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-[2-({[(2-methoxyphenyl)carbamoyl]methyl}sulfanyl)-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl]butanamide

K292-1343 Screening compound: N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-[2-({[(2-methoxyphenyl)carbamoyl]methyl}sulfanyl)-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl]butanamide
K292-1343 Screening compound: N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-[2-({[(2-methoxyphenyl)carbamoyl]methyl}sulfanyl)-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl]butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K292-1343
N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-[2-({[(2-methoxyphenyl)carbamoyl]methyl}sulfanyl)-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl]butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K292-1343

Molecular Formula

C27H26N4O6S2 (C27 H26 N4 O6 S2)

Compound Name

N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-[2-({[(2-methoxyphenyl)carbamoyl]methyl}sulfanyl)-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl]butanamide

IUPAC name

N-[(2H-13-benzodioxol-5-yl)methyl]-4-[2-({[(2-methoxyphenyl)carbamoyl]methyl}sulfanyl)-4-oxo-3H4H-thieno[32-d]pyrimidin-3-yl]butanamide

SMILES

COc(cccc1)c1NC(CSC(N(CCCC(NCc(cc1)cc2c1OCO2)=O)C1=O)=Nc2c1scc2)=O

InChI

InChI=1S/C27H26N4O6S2/c1-35-20-6-3-2-5-18(20)29-24(33)15-39-27-30-19-10-12-38-25(19)26(34)31(27)11-4-7-23(32)28-14-17-8-9-21-22(13-17)37-16-36-21/h2-3,5-6,8-10,12-13H,4,7,11,14-16H2,1H3,(H,28,32)(H,29,33)

InChI Key

WKEAPRYWUBFCQE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15091812

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

566.66

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

13.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.942

Distribution Coefficient, logD

2.942

Water Solubility, LogSw

-3.49

Polar Surface Area

98.437

Acid Dissociation Constant (pKa)

11.57

Base Dissociation Constant (pKb)

0.43

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.90

K292-1343 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with K292-1343 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K292-1343?
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What is the minimum amount of K292-1343 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K292-1343
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K292-1343
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K292-1343 available by request