K292-1363 Screening compound: N-[2-(3,4-dimethoxyphenyl)ethyl]-6-{4-oxo-2-[({4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methyl)sulfanyl]-3H,4H-thieno[3,2-d]pyrimidin-3-yl}hexanamide

K292-1363 Screening compound: N-[2-(3,4-dimethoxyphenyl)ethyl]-6-{4-oxo-2-[({4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methyl)sulfanyl]-3H,4H-thieno[3,2-d]pyrimidin-3-yl}hexanamide
K292-1363 Screening compound: N-[2-(3,4-dimethoxyphenyl)ethyl]-6-{4-oxo-2-[({4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methyl)sulfanyl]-3H,4H-thieno[3,2-d]pyrimidin-3-yl}hexanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K292-1363
N-[2-(3,4-dimethoxyphenyl)ethyl]-6-{4-oxo-2-[({4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methyl)sulfanyl]-3H,4H-thieno[3,2-d]pyrimidin-3-yl}hexanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K292-1363

Molecular Formula

C31H33N5O5S2 (C31 H33 N5 O5 S2)

Compound Name

N-[2-(3,4-dimethoxyphenyl)ethyl]-6-{4-oxo-2-[({4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methyl)sulfanyl]-3H,4H-thieno[3,2-d]pyrimidin-3-yl}hexanamide

IUPAC name

N-[2-(34-dimethoxyphenyl)ethyl]-6-{4-oxo-2-[({4-oxo-4H-pyrido[12-a]pyrimidin-2-yl}methyl)sulfanyl]-3H4H-thieno[32-d]pyrimidin-3-yl}hexanamide

SMILES

COc(ccc(CCNC(CCCCCN(C1=O)C(SCC(N=C2N3C=CC=C2)=CC3=O)=Nc2c1scc2)=O)c1)c1OC

InChI

InChI=1S/C31H33N5O5S2/c1-40-24-11-10-21(18-25(24)41-2)12-14-32-27(37)9-4-3-6-16-36-30(39)29-23(13-17-42-29)34-31(36)43-20-22-19-28(38)35-15-7-5-8-26(35)33-22/h5,7-8,10-11,13,15,17-19H,3-4,6,9,12,14,16,20H2,1-2H3,(H,32,37)

InChI Key

FBLIWZGTSDHQTQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15091829

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

619.77

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

15.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.674

Distribution Coefficient, logD

2.674

Water Solubility, LogSw

-3.08

Polar Surface Area

92.328

Acid Dissociation Constant (pKa)

14.38

Base Dissociation Constant (pKb)

1.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.30

K292-1363 in Drug Discovery

Included in Screening Libraries

CORONAVIRUS Library (20774 compounds)

Eccentric PPI Library (11937 compounds)

PLpro Library (6343 compounds)

Protein-Protein Interaction Library (218420 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with K292-1363 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K292-1363?
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What is the minimum amount of K292-1363 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K292-1363
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K292-1363
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K292-1363 available by request