K292-1626 Screening compound: 6-{2-[({[(4-methylphenyl)methyl]carbamoyl}methyl)sulfanyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl}hexanoic acid

K292-1626 Screening compound: 6-{2-[({[(4-methylphenyl)methyl]carbamoyl}methyl)sulfanyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl}hexanoic acid
K292-1626 Screening compound: 6-{2-[({[(4-methylphenyl)methyl]carbamoyl}methyl)sulfanyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl}hexanoic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound K292-1626
6-{2-[({[(4-methylphenyl)methyl]carbamoyl}methyl)sulfanyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl}hexanoic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K292-1626

Molecular Formula

C22H25N3O4S2 (C22 H25 N3 O4 S2)

Compound Name

6-{2-[({[(4-methylphenyl)methyl]carbamoyl}methyl)sulfanyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-3-yl}hexanoic acid

IUPAC name

6-{2-[({[(4-methylphenyl)methyl]carbamoyl}methyl)sulfanyl]-4-oxo-3H4H-thieno[32-d]pyrimidin-3-yl}hexanoic acid

SMILES

Cc1ccc(CNC(CSC(N(CCCCCC(O)=O)C2=O)=Nc3c2scc3)=O)cc1

InChI

InChI=1S/C22H25N3O4S2/c1-15-6-8-16(9-7-15)13-23-18(26)14-31-22-24-17-10-12-30-20(17)21(29)25(22)11-4-2-3-5-19(27)28/h6-10,12H,2-5,11,13-14H2,1H3,(H,23,26)(H,27,28)

InChI Key

ZNZJAHSGBFZNNR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15091955

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

459.59

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

12.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.105

Distribution Coefficient, logD

0.277

Water Solubility, LogSw

-3.30

Polar Surface Area

79.895

Acid Dissociation Constant (pKa)

4.57

Base Dissociation Constant (pKb)

-0.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

K292-1626 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with K292-1626 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K292-1626?
Check Price and Availability of K292-1626, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K292-1626 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K292-1626
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K292-1626
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K292-1626 available by request