K305-0358 Screening compound: 3-(4-fluorophenyl)-N,N,5-trimethyl-2,4-dioxo-1-({4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methyl)-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-6-carboxamide

K305-0358 Screening compound: 3-(4-fluorophenyl)-N,N,5-trimethyl-2,4-dioxo-1-({4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methyl)-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-6-carboxamide
K305-0358 Screening compound: 3-(4-fluorophenyl)-N,N,5-trimethyl-2,4-dioxo-1-({4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methyl)-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K305-0358
3-(4-fluorophenyl)-N,N,5-trimethyl-2,4-dioxo-1-({4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methyl)-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K305-0358

Molecular Formula

C25H20FN5O4S (C25 H20 FN5 O4 S)

Compound Name

3-(4-fluorophenyl)-N,N,5-trimethyl-2,4-dioxo-1-({4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methyl)-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-6-carboxamide

IUPAC name

3-(4-fluorophenyl)-NN5-trimethyl-24-dioxo-1-({4-oxo-4H-pyrido[12-a]pyrimidin-2-yl}methyl)-1H2H3H4H-thieno[23-d]pyrimidine-6-carboxamide

SMILES

Cc1c(C(N(C)C)=O)sc(N(CC(N=C2N3C=CC=C2)=CC3=O)C(N2c(cc3)ccc3F)=O)c1C2=O

InChI

InChI=1S/C25H20FN5O4S/c1-14-20-22(33)31(17-9-7-15(26)8-10-17)25(35)30(24(20)36-21(14)23(34)28(2)3)13-16-12-19(32)29-11-5-4-6-18(29)27-16/h4-12H,13H2,1-3H3

InChI Key

CDEMJWJTWXTSPS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15092933

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

505.53

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.445

Distribution Coefficient, logD

1.445

Water Solubility, LogSw

-2.30

Polar Surface Area

73.094

Acid Dissociation Constant (pKa)

25.98

Base Dissociation Constant (pKb)

0.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.00

K305-0358 in Drug Discovery

Included in Screening Libraries

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with K305-0358 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K305-0358?
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What is the minimum amount of K305-0358 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K305-0358
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K305-0358
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K305-0358 available by request