K306-0143 Screening compound: 3-chloro-6-{[4-phenyl-3,6-dihydro-1(2H)-pyridinyl]carbonyl}-11H-pyrido[2,1-b]quinazolin-11-one

K306-0143 Screening compound: 3-chloro-6-{[4-phenyl-3,6-dihydro-1(2H)-pyridinyl]carbonyl}-11H-pyrido[2,1-b]quinazolin-11-one
K306-0143 Screening compound: 3-chloro-6-{[4-phenyl-3,6-dihydro-1(2H)-pyridinyl]carbonyl}-11H-pyrido[2,1-b]quinazolin-11-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K306-0143
3-chloro-6-{[4-phenyl-3,6-dihydro-1(2H)-pyridinyl]carbonyl}-11H-pyrido[2,1-b]quinazolin-11-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K306-0143

Molecular Formula

C24H18ClN3O2 (C24 H18 ClN3 O2)

Compound Name

3-chloro-6-{[4-phenyl-3,6-dihydro-1(2H)-pyridinyl]carbonyl}-11H-pyrido[2,1-b]quinazolin-11-one

IUPAC name

n/a

SMILES

O=C(C(C1=Nc2c3ccc(Cl)c2)=CC=CN1C3=O)N(CC1)CC=C1c1ccccc1

InChI

InChI=1S/C24H18ClN3O2/c25-18-8-9-19-21(15-18)26-22-20(7-4-12-28(22)24(19)30)23(29)27-13-10-17(11-14-27)16-5-2-1-3-6-16/h1-10,12,15H,11,13-14H2

InChI Key

GJRJVGJLKIVSRN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15093074

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

415.88

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.863

Distribution Coefficient, logD

3.863

Water Solubility, LogSw

-4.42

Polar Surface Area

40.882

Acid Dissociation Constant (pKa)

28.52

Base Dissociation Constant (pKb)

-3.53

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

K306-0143 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K306-0143 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K306-0143?
Check Price and Availability of K306-0143, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K306-0143 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K306-0143
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K306-0143
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K306-0143 available by request