K306-0158 Screening compound: 1'-{3-chloro-11-oxo-11H-pyrido[2,1-b]quinazoline-6-carbonyl}-[1,4'-bipiperidine]-4-carboxamide

K306-0158 Screening compound: 1'-{3-chloro-11-oxo-11H-pyrido[2,1-b]quinazoline-6-carbonyl}-[1,4'-bipiperidine]-4-carboxamide
K306-0158 Screening compound: 1'-{3-chloro-11-oxo-11H-pyrido[2,1-b]quinazoline-6-carbonyl}-[1,4'-bipiperidine]-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K306-0158
1'-{3-chloro-11-oxo-11H-pyrido[2,1-b]quinazoline-6-carbonyl}-[1,4'-bipiperidine]-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K306-0158

Molecular Formula

C24H26ClN5O3 (C24 H26 ClN5 O3)

Compound Name

1'-{3-chloro-11-oxo-11H-pyrido[2,1-b]quinazoline-6-carbonyl}-[1,4'-bipiperidine]-4-carboxamide

IUPAC name

1'-{3-chloro-11-oxo-11H-pyrido[21-b]quinazoline-6-carbonyl}-[14'-bipiperidine]-4-carboxamide

SMILES

NC(C(CC1)CCN1C(CC1)CCN1C(C(C1=Nc2c3ccc(Cl)c2)=CC=CN1C3=O)=O)=O

InChI

InChI=1S/C24H26ClN5O3/c25-16-3-4-18-20(14-16)27-22-19(2-1-9-30(22)24(18)33)23(32)29-12-7-17(8-13-29)28-10-5-15(6-11-28)21(26)31/h1-4,9,14-15,17H,5-8,10-13H2,(H2,26,31)

InChI Key

BLVQXFJRDLSJFM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05027864

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

467.96

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.142

Distribution Coefficient, logD

-3.039

Water Solubility, LogSw

-2.66

Polar Surface Area

78.306

Acid Dissociation Constant (pKa)

14.92

Base Dissociation Constant (pKb)

11.58

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

K306-0158 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K306-0158 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K306-0158?
Check Price and Availability of K306-0158, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K306-0158 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K306-0158
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K306-0158
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K306-0158 available by request