K308-0085 Screening compound: 8-{4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonyl}-11H-pyrido[2,1-b]quinazolin-11-one

K308-0085 Screening compound: 8-{4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonyl}-11H-pyrido[2,1-b]quinazolin-11-one
K308-0085 Screening compound: 8-{4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonyl}-11H-pyrido[2,1-b]quinazolin-11-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K308-0085
8-{4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonyl}-11H-pyrido[2,1-b]quinazolin-11-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K308-0085

Molecular Formula

C24H19F3N4O2 (C24 H19 F3 N4 O2)

Compound Name

8-{4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonyl}-11H-pyrido[2,1-b]quinazolin-11-one

IUPAC name

8-{4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonyl}-11H-pyrido[21-b]quinazolin-11-one

SMILES

O=C(C(C=CC1=Nc2c3cccc2)=CN1C3=O)N(CC1)CCN1c1cccc(C(F)(F)F)c1

InChI

InChI=1S/C24H19F3N4O2/c25-24(26,27)17-4-3-5-18(14-17)29-10-12-30(13-11-29)22(32)16-8-9-21-28-20-7-2-1-6-19(20)23(33)31(21)15-16/h1-9,14-15H,10-13H2

InChI Key

JKEWHJNAIWSMCA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15093156

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

452.44

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.891

Distribution Coefficient, logD

2.891

Water Solubility, LogSw

-3.70

Polar Surface Area

45.912

Acid Dissociation Constant (pKa)

28.55

Base Dissociation Constant (pKb)

2.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

References: we are preparing a list of scientific research reports with K308-0085 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K308-0085?
Check Price and Availability of K308-0085, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K308-0085 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K308-0085
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K308-0085
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K308-0085 available by request