K402-0377 Screening compound: 1,3-dimethyl 5-{[1-(2,4-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}benzene-1,3-dicarboxylate

K402-0377 Screening compound: 1,3-dimethyl 5-{[1-(2,4-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}benzene-1,3-dicarboxylate
K402-0377 Screening compound: 1,3-dimethyl 5-{[1-(2,4-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}benzene-1,3-dicarboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound K402-0377
1,3-dimethyl 5-{[1-(2,4-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}benzene-1,3-dicarboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K402-0377

Molecular Formula

C23H21N5O4 (C23 H21 N5 O4)

Compound Name

1,3-dimethyl 5-{[1-(2,4-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}benzene-1,3-dicarboxylate

IUPAC name

13-dimethyl 5-{[1-(24-dimethylphenyl)-1H-pyrazolo[34-d]pyrimidin-4-yl]amino}benzene-13-dicarboxylate

SMILES

Cc(cc1)cc(C)c1-n1ncc2c1ncnc2Nc1cc(C(OC)=O)cc(C(OC)=O)c1

InChI

InChI=1S/C23H21N5O4/c1-13-5-6-19(14(2)7-13)28-21-18(11-26-28)20(24-12-25-21)27-17-9-15(22(29)31-3)8-16(10-17)23(30)32-4/h5-12H,1-4H3,(H,24,25,27)

InChI Key

WEHDBKSIMGZNAY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04449373

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

431.45

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

5.658

Distribution Coefficient, logD

5.657

Water Solubility, LogSw

-5.53

Polar Surface Area

86.074

Acid Dissociation Constant (pKa)

16.75

Base Dissociation Constant (pKb)

4.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

K402-0377 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K402-0377 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K402-0377?
Check Price and Availability of K402-0377, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K402-0377 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K402-0377
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K402-0377
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K402-0377 available by request