K405-2994 Screening compound: 4-(4-ethylpiperazino)-1-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine

K405-2994 Screening compound: 4-(4-ethylpiperazino)-1-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine
K405-2994 Screening compound: 4-(4-ethylpiperazino)-1-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound K405-2994
4-(4-ethylpiperazino)-1-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K405-2994

Molecular Formula

C17H19FN6 (C17 H19 FN6)

Compound Name

4-(4-ethylpiperazino)-1-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine

IUPAC name

1-ethyl-4-[1-(4-fluorophenyl)-1H-pyrazolo[34-d]pyrimidin-4-yl]piperazine

SMILES

CCN(CC1)CCN1c1c(cnn2-c(cc3)ccc3F)c2ncn1

InChI

InChI=1S/C17H19FN6/c1-2-22-7-9-23(10-8-22)16-15-11-21-24(17(15)20-12-19-16)14-5-3-13(18)4-6-14/h3-6,11-12H,2,7-10H2,1H3

InChI Key

QIOHEDOKUHHKRD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05955853

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

326.38

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.950

Distribution Coefficient, logD

2.379

Water Solubility, LogSw

-2.80

Polar Surface Area

41.397

Acid Dissociation Constant (pKa)

21.41

Base Dissociation Constant (pKb)

7.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.29

K405-2994 in Drug Discovery

Included in Screening Libraries

Antiviral Annotated Library (21441 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K405-2994 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K405-2994?
Check Price and Availability of K405-2994, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K405-2994 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K405-2994
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K405-2994
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K405-2994 available by request