K405-3235 Screening compound: 1-[1-(3-chloro-4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-4-(4-fluorophenyl)piperazine

K405-3235 Screening compound: 1-[1-(3-chloro-4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-4-(4-fluorophenyl)piperazine
K405-3235 Screening compound: 1-[1-(3-chloro-4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-4-(4-fluorophenyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound K405-3235
1-[1-(3-chloro-4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-4-(4-fluorophenyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K405-3235

Molecular Formula

C22H20ClFN6 (C22 H20 ClFN6)

Compound Name

1-[1-(3-chloro-4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-4-(4-fluorophenyl)piperazine

IUPAC name

1-[1-(3-chloro-4-methylphenyl)-1H-pyrazolo[34-d]pyrimidin-4-yl]-4-(4-fluorophenyl)piperazine

SMILES

Cc(ccc(-n1ncc2c(N(CC3)CCN3c(cc3)ccc3F)ncnc12)c1)c1Cl

InChI

InChI=1S/C22H20ClFN6/c1-15-2-5-18(12-20(15)23)30-22-19(13-27-30)21(25-14-26-22)29-10-8-28(9-11-29)17-6-3-16(24)4-7-17/h2-7,12-14H,8-11H2,1H3

InChI Key

RYUIWODELNGSOM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05956155

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

422.89

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.794

Distribution Coefficient, logD

5.793

Water Solubility, LogSw

-6.17

Polar Surface Area

41.121

Acid Dissociation Constant (pKa)

21.21

Base Dissociation Constant (pKb)

4.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

K405-3235 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with K405-3235 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K405-3235?
Check Price and Availability of K405-3235, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K405-3235 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K405-3235
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K405-3235
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K405-3235 available by request