K405-3536 Screening compound: 2-[(2-{[1-(5-chloro-2-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}ethyl)amino]ethan-1-ol

K405-3536 Screening compound: 2-[(2-{[1-(5-chloro-2-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}ethyl)amino]ethan-1-ol
K405-3536 Screening compound: 2-[(2-{[1-(5-chloro-2-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}ethyl)amino]ethan-1-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound K405-3536
2-[(2-{[1-(5-chloro-2-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}ethyl)amino]ethan-1-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K405-3536

Molecular Formula

C16H19ClN6O (C16 H19 ClN6 O)

Compound Name

2-[(2-{[1-(5-chloro-2-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}ethyl)amino]ethan-1-ol

IUPAC name

2-[(2-{[1-(5-chloro-2-methylphenyl)-1H-pyrazolo[34-d]pyrimidin-4-yl]amino}ethyl)amino]ethan-1-ol

SMILES

Cc(ccc(Cl)c1)c1-n1ncc2c(NCCNCCO)ncnc12

InChI

InChI=1S/C16H19ClN6O/c1-11-2-3-12(17)8-14(11)23-16-13(9-22-23)15(20-10-21-16)19-5-4-18-6-7-24/h2-3,8-10,18,24H,4-7H2,1H3,(H,19,20,21)

InChI Key

PDQVVRJSXJMEMS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05956548

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

346.82

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.021

Distribution Coefficient, logD

0.300

Water Solubility, LogSw

-2.20

Polar Surface Area

73.538

Acid Dissociation Constant (pKa)

15.07

Base Dissociation Constant (pKb)

9.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.30

K405-3536 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Others
  • GPCR
  • Phosphatases
Mechanism of action:
  • Epigenetic
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K405-3536 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K405-3536?
Check Price and Availability of K405-3536, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K405-3536 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K405-3536
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K405-3536
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K405-3536 available by request