K405-4271 Screening compound: 1-[1-(2-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-4-phenylpiperazine

K405-4271 Screening compound: 1-[1-(2-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-4-phenylpiperazine
K405-4271 Screening compound: 1-[1-(2-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-4-phenylpiperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound K405-4271
1-[1-(2-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-4-phenylpiperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K405-4271

Molecular Formula

C21H19ClN6 (C21 H19 ClN6)

Compound Name

1-[1-(2-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-4-phenylpiperazine

IUPAC name

1-[1-(2-chlorophenyl)-1H-pyrazolo[34-d]pyrimidin-4-yl]-4-phenylpiperazine

SMILES

Clc(cccc1)c1-n1ncc2c(N(CC3)CCN3c3ccccc3)ncnc12

InChI

InChI=1S/C21H19ClN6/c22-18-8-4-5-9-19(18)28-21-17(14-25-28)20(23-15-24-21)27-12-10-26(11-13-27)16-6-2-1-3-7-16/h1-9,14-15H,10-13H2

InChI Key

SGYFBFCGGRVRMP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09240623

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

390.88

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.810

Distribution Coefficient, logD

4.809

Water Solubility, LogSw

-5.00

Polar Surface Area

40.820

Acid Dissociation Constant (pKa)

21.21

Base Dissociation Constant (pKb)

4.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

K405-4271 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

CNS Targets (44014 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Protein-Protein Interaction Library (218420 compounds)

STING Agonist Library (5895 compounds)

Targeted Diversity Library (40567 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Immune system
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Others
  • Ion Channels
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with K405-4271 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K405-4271?
Check Price and Availability of K405-4271, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K405-4271 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K405-4271
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K405-4271
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K405-4271 available by request