K410-0133 Screening compound: N~1~-[2-(2-methylphenyl)-5,5-dioxo-2,4,5,6-tetrahydro-5lambda~6~-thieno[3,4-c]pyrazol-3-yl]-2-(trifluoromethyl)benzamide

K410-0133 Screening compound: N~1~-[2-(2-methylphenyl)-5,5-dioxo-2,4,5,6-tetrahydro-5lambda~6~-thieno[3,4-c]pyrazol-3-yl]-2-(trifluoromethyl)benzamide
K410-0133 Screening compound: N~1~-[2-(2-methylphenyl)-5,5-dioxo-2,4,5,6-tetrahydro-5lambda~6~-thieno[3,4-c]pyrazol-3-yl]-2-(trifluoromethyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K410-0133
N~1~-[2-(2-methylphenyl)-5,5-dioxo-2,4,5,6-tetrahydro-5lambda~6~-thieno[3,4-c]pyrazol-3-yl]-2-(trifluoromethyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K410-0133

Molecular Formula

C20H16F3N3O3S (C20 H16 F3 N3 O3 S)

Compound Name

N~1~-[2-(2-methylphenyl)-5,5-dioxo-2,4,5,6-tetrahydro-5lambda~6~-thieno[3,4-c]pyrazol-3-yl]-2-(trifluoromethyl)benzamide

IUPAC name

N-[2-(2-methylphenyl)-55-dioxo-2H4H6H-5lambda6-thieno[34-c]pyrazol-3-yl]-2-(trifluoromethyl)benzamide

SMILES

Cc(cccc1)c1-n1nc(CS(C2)(=O)=O)c2c1NC(c1c(C(F)(F)F)cccc1)=O

InChI

InChI=1S/C20H16F3N3O3S/c1-12-6-2-5-9-17(12)26-18(14-10-30(28,29)11-16(14)25-26)24-19(27)13-7-3-4-8-15(13)20(21,22)23/h2-9H,10-11H2,1H3,(H,24,27)

InChI Key

PVEFPIOOCKBVLM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04451962

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

435.43

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.900

Distribution Coefficient, logD

1.431

Water Solubility, LogSw

-3.76

Polar Surface Area

66.400

Acid Dissociation Constant (pKa)

5.95

Base Dissociation Constant (pKb)

-3.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

K410-0133 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Mechanism of action:
  • Epigenetic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K410-0133 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K410-0133?
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What is the minimum amount of K410-0133 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K410-0133
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K410-0133
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K410-0133 available by request