K600-0221 Screening compound: N-[(4-chlorophenyl)methyl]-2-(4-fluorophenyl)quinoline-4-carboxamide

K600-0221 Screening compound: N-[(4-chlorophenyl)methyl]-2-(4-fluorophenyl)quinoline-4-carboxamide
K600-0221 Screening compound: N-[(4-chlorophenyl)methyl]-2-(4-fluorophenyl)quinoline-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K600-0221
N-[(4-chlorophenyl)methyl]-2-(4-fluorophenyl)quinoline-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K600-0221

Molecular Formula

C23H16ClFN2O (C23 H16 ClFN2 O)

Compound Name

N-[(4-chlorophenyl)methyl]-2-(4-fluorophenyl)quinoline-4-carboxamide

IUPAC name

N-[(4-chlorophenyl)methyl]-2-(4-fluorophenyl)quinoline-4-carboxamide

SMILES

O=C(c1cc(-c(cc2)ccc2F)nc2ccccc12)NCc(cc1)ccc1Cl

InChI

InChI=1S/C23H16ClFN2O/c24-17-9-5-15(6-10-17)14-26-23(28)20-13-22(16-7-11-18(25)12-8-16)27-21-4-2-1-3-19(20)21/h1-13H,14H2,(H,26,28)

InChI Key

TXBFXTPIMRXGHJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02088868

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

390.84

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

6.143

Distribution Coefficient, logD

6.143

Water Solubility, LogSw

-6.30

Polar Surface Area

32.711

Acid Dissociation Constant (pKa)

12.98

Base Dissociation Constant (pKb)

2.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.30

K600-0221 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K600-0221 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K600-0221?
Check Price and Availability of K600-0221, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K600-0221 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K600-0221
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K600-0221
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K600-0221 available by request