K601-0350 Screening compound: 4-[4-(3-chlorophenyl)piperazine-1-carbonyl]-2-[4-(4-fluorophenyl)piperazin-1-yl]quinoline

K601-0350 Screening compound: 4-[4-(3-chlorophenyl)piperazine-1-carbonyl]-2-[4-(4-fluorophenyl)piperazin-1-yl]quinoline
K601-0350 Screening compound: 4-[4-(3-chlorophenyl)piperazine-1-carbonyl]-2-[4-(4-fluorophenyl)piperazin-1-yl]quinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound K601-0350
4-[4-(3-chlorophenyl)piperazine-1-carbonyl]-2-[4-(4-fluorophenyl)piperazin-1-yl]quinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K601-0350

Molecular Formula

C30H29ClFN5O (C30 H29 ClFN5 O)

Compound Name

4-[4-(3-chlorophenyl)piperazine-1-carbonyl]-2-[4-(4-fluorophenyl)piperazin-1-yl]quinoline

IUPAC name

4-[4-(3-chlorophenyl)piperazine-1-carbonyl]-2-[4-(4-fluorophenyl)piperazin-1-yl]quinoline

SMILES

O=C(c1cc(N(CC2)CCN2c(cc2)ccc2F)nc2ccccc12)N(CC1)CCN1c1cccc(Cl)c1

InChI

InChI=1S/C30H29ClFN5O/c31-22-4-3-5-25(20-22)35-14-18-37(19-15-35)30(38)27-21-29(33-28-7-2-1-6-26(27)28)36-16-12-34(13-17-36)24-10-8-23(32)9-11-24/h1-11,20-21H,12-19H2

InChI Key

VEIACVKAYLWHBR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02652079

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

530.04

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

6.312

Distribution Coefficient, logD

6.311

Water Solubility, LogSw

-6.38

Polar Surface Area

34.654

Acid Dissociation Constant (pKa)

24.44

Base Dissociation Constant (pKb)

4.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.70

K601-0350 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with K601-0350 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K601-0350?
Check Price and Availability of K601-0350, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K601-0350 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K601-0350
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K601-0350
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K601-0350 available by request