K607-0627 Screening compound: 5-{3'-fluoro-4'-propoxy-[1,1'-biphenyl]-4-yl}-3-(4-methylphenyl)-1,2,4-oxadiazole

K607-0627 Screening compound: 5-{3'-fluoro-4'-propoxy-[1,1'-biphenyl]-4-yl}-3-(4-methylphenyl)-1,2,4-oxadiazole
K607-0627 Screening compound: 5-{3'-fluoro-4'-propoxy-[1,1'-biphenyl]-4-yl}-3-(4-methylphenyl)-1,2,4-oxadiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound K607-0627
5-{3'-fluoro-4'-propoxy-[1,1'-biphenyl]-4-yl}-3-(4-methylphenyl)-1,2,4-oxadiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K607-0627

Molecular Formula

C24H21FN2O2 (C24 H21 FN2 O2)

Compound Name

5-{3'-fluoro-4'-propoxy-[1,1'-biphenyl]-4-yl}-3-(4-methylphenyl)-1,2,4-oxadiazole

IUPAC name

5-{3'-fluoro-4'-propoxy-[11'-biphenyl]-4-yl}-3-(4-methylphenyl)-124-oxadiazole

SMILES

CCCOc(ccc(-c(cc1)ccc1-c1nc(-c2ccc(C)cc2)no1)c1)c1F

InChI

InChI=1S/C24H21FN2O2/c1-3-14-28-22-13-12-20(15-21(22)25)17-8-10-19(11-9-17)24-26-23(27-29-24)18-6-4-16(2)5-7-18/h4-13,15H,3,14H2,1-2H3

InChI Key

ZLOQNDXNCYTLLB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15093320

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

7.563

Distribution Coefficient, logD

7.563

Water Solubility, LogSw

-5.90

Polar Surface Area

38.877

Acid Dissociation Constant (pKa)

27.49

Base Dissociation Constant (pKb)

-6.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

K607-0627 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PD-1/L1 Library (498 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Others
  • Phosphatases

References: we are preparing a list of scientific research reports with K607-0627 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K607-0627?
Check Price and Availability of K607-0627, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K607-0627 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K607-0627
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K607-0627
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K607-0627 available by request