K610-0283 Screening compound: 5-(4-chlorophenyl)-N-[2-(1H-indol-3-yl)ethyl]-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-2-carboxamide

K610-0283 Screening compound: 5-(4-chlorophenyl)-N-[2-(1H-indol-3-yl)ethyl]-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-2-carboxamide
K610-0283 Screening compound: 5-(4-chlorophenyl)-N-[2-(1H-indol-3-yl)ethyl]-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K610-0283
5-(4-chlorophenyl)-N-[2-(1H-indol-3-yl)ethyl]-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K610-0283

Molecular Formula

C24H21ClF3N5O (C24 H21 ClF3 N5 O)

Compound Name

5-(4-chlorophenyl)-N-[2-(1H-indol-3-yl)ethyl]-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-2-carboxamide

IUPAC name

5-(4-chlorophenyl)-N-[2-(1H-indol-3-yl)ethyl]-7-(trifluoromethyl)-4H5H6H7H-pyrazolo[15-a]pyrimidine-2-carboxamide

SMILES

O=C(c1nn(C(CC(c(cc2)ccc2Cl)N2)C(F)(F)F)c2c1)NCCc1c[nH]c2c1cccc2

InChI

InChI=1S/C24H21ClF3N5O/c25-16-7-5-14(6-8-16)19-11-21(24(26,27)28)33-22(31-19)12-20(32-33)23(34)29-10-9-15-13-30-18-4-2-1-3-17(15)18/h1-8,12-13,19,21,30-31H,9-11H2,(H,29,34)

InChI Key

NDQIAVWAEABHPT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02089191

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

487.91

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.183

Distribution Coefficient, logD

5.183

Water Solubility, LogSw

-5.93

Polar Surface Area

61.892

Acid Dissociation Constant (pKa)

14.42

Base Dissociation Constant (pKb)

-2.00

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

25.00

K610-0283 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with K610-0283 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K610-0283?
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What is the minimum amount of K610-0283 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K610-0283
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K610-0283
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K610-0283 available by request