K610-0376 Screening compound: N-[(2-chlorophenyl)methyl]-5-(3,4-dimethoxyphenyl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-3-carboxamide

K610-0376 Screening compound: N-[(2-chlorophenyl)methyl]-5-(3,4-dimethoxyphenyl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-3-carboxamide
K610-0376 Screening compound: N-[(2-chlorophenyl)methyl]-5-(3,4-dimethoxyphenyl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K610-0376
N-[(2-chlorophenyl)methyl]-5-(3,4-dimethoxyphenyl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K610-0376

Molecular Formula

C23H22ClF3N4O3 (C23 H22 ClF3 N4 O3)

Compound Name

N-[(2-chlorophenyl)methyl]-5-(3,4-dimethoxyphenyl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-3-carboxamide

IUPAC name

(5R7S)-N-[(2-chlorophenyl)methyl]-5-(34-dimethoxyphenyl)-7-(trifluoromethyl)-4H5H6H7H-pyrazolo[15-a]pyrimidine-3-carboxamide

SMILES

COc(ccc([C@H](C[C@H](C(F)(F)F)n1nc2)Nc1c2C(NCc(cccc1)c1Cl)=O)c1)c1OC

InChI

InChI=1S/C23H22ClF3N4O3/c1-33-18-8-7-13(9-19(18)34-2)17-10-20(23(25,26)27)31-21(30-17)15(12-29-31)22(32)28-11-14-5-3-4-6-16(14)24/h3-9,12,17,20,30H,10-11H2,1-2H3,(H,28,32)/t17-,20-/m1/s1

InChI Key

GDTOLYYCIUZBMB-YLJYHZDGSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

494.9

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.688

Distribution Coefficient, logD

4.688

Water Solubility, LogSw

-4.93

Polar Surface Area

65.188

Acid Dissociation Constant (pKa)

12.57

Base Dissociation Constant (pKb)

-0.81

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

30.40

K610-0376 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anti-infective Library (19449 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal

References: we are preparing a list of scientific research reports with K610-0376 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K610-0376?
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What is the minimum amount of K610-0376 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K610-0376
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K610-0376
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K610-0376 available by request