K610-0447 Screening compound: N-(5-chloro-2-methoxyphenyl)-5-(4-methylphenyl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-3-carboxamide

K610-0447 Screening compound: N-(5-chloro-2-methoxyphenyl)-5-(4-methylphenyl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-3-carboxamide
K610-0447 Screening compound: N-(5-chloro-2-methoxyphenyl)-5-(4-methylphenyl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K610-0447
N-(5-chloro-2-methoxyphenyl)-5-(4-methylphenyl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K610-0447

Molecular Formula

C22H20ClF3N4O2 (C22 H20 ClF3 N4 O2)

Compound Name

N-(5-chloro-2-methoxyphenyl)-5-(4-methylphenyl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-3-carboxamide

IUPAC name

(5R7S)-N-(5-chloro-2-methoxyphenyl)-5-(4-methylphenyl)-7-(trifluoromethyl)-4H5H6H7H-pyrazolo[15-a]pyrimidine-3-carboxamide

SMILES

Cc1ccc([C@H](C[C@H](C(F)(F)F)n2nc3)Nc2c3C(Nc(cc(cc2)Cl)c2OC)=O)cc1

InChI

InChI=1S/C22H20ClF3N4O2/c1-12-3-5-13(6-4-12)16-10-19(22(24,25)26)30-20(28-16)15(11-27-30)21(31)29-17-9-14(23)7-8-18(17)32-2/h3-9,11,16,19,28H,10H2,1-2H3,(H,29,31)/t16-,19-/m1/s1

InChI Key

YFSJQHIGPFQHPY-VQIMIIECSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

464.87

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.241

Distribution Coefficient, logD

5.223

Water Solubility, LogSw

-5.63

Polar Surface Area

55.538

Acid Dissociation Constant (pKa)

8.76

Base Dissociation Constant (pKb)

-2.15

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

27.30

References: we are preparing a list of scientific research reports with K610-0447 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K610-0447?
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What is the minimum amount of K610-0447 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K610-0447
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K610-0447
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K610-0447 available by request