K623-0320 Screening compound: N~1~-[5-(1-azepanylcarbonyl)-2-(6-oxo-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-11-yl)phenyl]-2-(2-chloro-6-fluorophenyl)acetamide

K623-0320 Screening compound: N~1~-[5-(1-azepanylcarbonyl)-2-(6-oxo-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-11-yl)phenyl]-2-(2-chloro-6-fluorophenyl)acetamide
K623-0320 Screening compound: N~1~-[5-(1-azepanylcarbonyl)-2-(6-oxo-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-11-yl)phenyl]-2-(2-chloro-6-fluorophenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K623-0320
N~1~-[5-(1-azepanylcarbonyl)-2-(6-oxo-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-11-yl)phenyl]-2-(2-chloro-6-fluorophenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K623-0320

Molecular Formula

C32H34ClFN4O3 (C32 H34 ClFN4 O3)

Compound Name

N~1~-[5-(1-azepanylcarbonyl)-2-(6-oxo-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-11-yl)phenyl]-2-(2-chloro-6-fluorophenyl)acetamide

IUPAC name

N-[5-(azepane-1-carbonyl)-2-{6-oxo-711-diazatricyclo[7.3.1.0^{27}]trideca-24-dien-11-yl}phenyl]-2-(2-chloro-6-fluorophenyl)acetamide

SMILES

O=C(Cc(c(F)ccc1)c1Cl)Nc(cc(cc1)C(N2CCCCCC2)=O)c1N(CC(C1)CN23)CC1C3=CC=CC2=O

InChI

InChI=1S/C32H34ClFN4O3/c33-25-7-5-8-26(34)24(25)17-30(39)35-27-16-22(32(41)36-13-3-1-2-4-14-36)11-12-29(27)37-18-21-15-23(20-37)28-9-6-10-31(40)38(28)19-21/h5-12,16,21,23H,1-4,13-15,17-20H2,(H,35,39)

InChI Key

OMRLZUXXTAWCTO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15093389

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

577.1

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.234

Distribution Coefficient, logD

5.228

Water Solubility, LogSw

-5.81

Polar Surface Area

58.248

Acid Dissociation Constant (pKa)

9.32

Base Dissociation Constant (pKb)

1.86

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

40.60

K623-0320 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Lipid Metabolism Library (9174 compounds)

Protein-Protein Interaction Library (218420 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cardiovascular
  • Metabolic
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with K623-0320 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K623-0320?
Check Price and Availability of K623-0320, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K623-0320 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K623-0320
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K623-0320
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K623-0320 available by request