K623-0367 Screening compound: 3,5-dimethoxy-N~1~-[5-[(2-methylpiperidino)carbonyl]-2-(6-oxo-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-11-yl)phenyl]benzamide

K623-0367 Screening compound: 3,5-dimethoxy-N~1~-[5-[(2-methylpiperidino)carbonyl]-2-(6-oxo-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-11-yl)phenyl]benzamide
K623-0367 Screening compound: 3,5-dimethoxy-N~1~-[5-[(2-methylpiperidino)carbonyl]-2-(6-oxo-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-11-yl)phenyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K623-0367
3,5-dimethoxy-N~1~-[5-[(2-methylpiperidino)carbonyl]-2-(6-oxo-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-11-yl)phenyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K623-0367

Molecular Formula

C33H38N4O5 (C33 H38 N4 O5)

Compound Name

3,5-dimethoxy-N~1~-[5-[(2-methylpiperidino)carbonyl]-2-(6-oxo-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-11-yl)phenyl]benzamide

IUPAC name

35-dimethoxy-N-[5-(2-methylpiperidine-1-carbonyl)-2-{6-oxo-711-diazatricyclo[7.3.1.0^{27}]trideca-24-dien-11-yl}phenyl]benzamide

SMILES

CC(CCCC1)N1C(c(cc1)cc(NC(c2cc(OC)cc(OC)c2)=O)c1N(CC(C1)CN23)CC1C3=CC=CC2=O)=O

InChI

InChI=1S/C33H38N4O5/c1-21-7-4-5-12-36(21)33(40)23-10-11-30(28(16-23)34-32(39)24-14-26(41-2)17-27(15-24)42-3)35-18-22-13-25(20-35)29-8-6-9-31(38)37(29)19-22/h6,8-11,14-17,21-22,25H,4-5,7,12-13,18-20H2,1-3H3,(H,34,39)

InChI Key

WCSLYTGVKYUJGY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02657044

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

570.69

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.967

Distribution Coefficient, logD

4.964

Water Solubility, LogSw

-4.56

Polar Surface Area

72.503

Acid Dissociation Constant (pKa)

9.65

Base Dissociation Constant (pKb)

-0.11

Number of Chiral Centers

3.00

Percent sp3 carbon bonding

42.40

K623-0367 in Drug Discovery

Included in Screening Libraries

Lipid Metabolism Library (9174 compounds)

Protein-Protein Interaction Library (218420 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Metabolic
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with K623-0367 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K623-0367?
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What is the minimum amount of K623-0367 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K623-0367
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K623-0367
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K623-0367 available by request