K655-0273 Screening compound: 2-chloro-N~1~-cyclohexyl-5-(3,5-dioxo-4-azatricyclo[5.2.1.0~2,6~]dec-4-yl)-N~1~-methylbenzamide

K655-0273 Screening compound: 2-chloro-N~1~-cyclohexyl-5-(3,5-dioxo-4-azatricyclo[5.2.1.0~2,6~]dec-4-yl)-N~1~-methylbenzamide
K655-0273 Screening compound: 2-chloro-N~1~-cyclohexyl-5-(3,5-dioxo-4-azatricyclo[5.2.1.0~2,6~]dec-4-yl)-N~1~-methylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K655-0273
2-chloro-N~1~-cyclohexyl-5-(3,5-dioxo-4-azatricyclo[5.2.1.0~2,6~]dec-4-yl)-N~1~-methylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K655-0273

Molecular Formula

C23H27ClN2O3 (C23 H27 ClN2 O3)

Compound Name

2-chloro-N~1~-cyclohexyl-5-(3,5-dioxo-4-azatricyclo[5.2.1.0~2,6~]dec-4-yl)-N~1~-methylbenzamide

IUPAC name

2-chloro-N-cyclohexyl-5-{35-dioxo-4-azatricyclo[5.2.1.0^{26}]decan-4-yl}-N-methylbenzamide

SMILES

CN(C1CCCCC1)C(c(cc(cc1)N(C(C2C3C4CC2CC4)=O)C3=O)c1Cl)=O

InChI

InChI=1S/C23H27ClN2O3/c1-25(15-5-3-2-4-6-15)21(27)17-12-16(9-10-18(17)24)26-22(28)19-13-7-8-14(11-13)20(19)23(26)29/h9-10,12-15,19-20H,2-8,11H2,1H3

InChI Key

AJPPFZYYCSRQOF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02652815

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

414.93

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.160

Distribution Coefficient, logD

3.160

Water Solubility, LogSw

-3.66

Polar Surface Area

44.927

Acid Dissociation Constant (pKa)

17.54

Base Dissociation Constant (pKb)

-1.46

Number of Chiral Centers

4.00

Percent sp3 carbon bonding

60.90

K655-0273 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

Anti-HIV1 Library (19540 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Proteases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with K655-0273 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K655-0273?
Check Price and Availability of K655-0273, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K655-0273 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K655-0273
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K655-0273
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K655-0273 available by request