K781-1482 Screening compound: 5-(4-acetylpiperazine-1-carbonyl)-2-{[(4-fluorophenyl)methyl]amino}-N-[3-(trifluoromethyl)phenyl]benzene-1-sulfonamide

K781-1482 Screening compound: 5-(4-acetylpiperazine-1-carbonyl)-2-{[(4-fluorophenyl)methyl]amino}-N-[3-(trifluoromethyl)phenyl]benzene-1-sulfonamide
K781-1482 Screening compound: 5-(4-acetylpiperazine-1-carbonyl)-2-{[(4-fluorophenyl)methyl]amino}-N-[3-(trifluoromethyl)phenyl]benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K781-1482
5-(4-acetylpiperazine-1-carbonyl)-2-{[(4-fluorophenyl)methyl]amino}-N-[3-(trifluoromethyl)phenyl]benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K781-1482

Molecular Formula

C27H26F4N4O4S (C27 H26 F4 N4 O4 S)

Compound Name

5-(4-acetylpiperazine-1-carbonyl)-2-{[(4-fluorophenyl)methyl]amino}-N-[3-(trifluoromethyl)phenyl]benzene-1-sulfonamide

IUPAC name

5-(4-acetylpiperazine-1-carbonyl)-2-{[(4-fluorophenyl)methyl]amino}-N-[3-(trifluoromethyl)phenyl]benzene-1-sulfonamide

SMILES

CC(N(CC1)CCN1C(c(cc1)cc(S(Nc2cc(C(F)(F)F)ccc2)(=O)=O)c1NCc(cc1)ccc1F)=O)=O

InChI

InChI=1S/C27H26F4N4O4S/c1-18(36)34-11-13-35(14-12-34)26(37)20-7-10-24(32-17-19-5-8-22(28)9-6-19)25(15-20)40(38,39)33-23-4-2-3-21(16-23)27(29,30)31/h2-10,15-16,32-33H,11-14,17H2,1H3

InChI Key

KBPYIQAOGMXISP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15093869

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

578.59

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.565

Distribution Coefficient, logD

1.816

Water Solubility, LogSw

-3.85

Polar Surface Area

84.269

Acid Dissociation Constant (pKa)

5.66

Base Dissociation Constant (pKb)

-2.99

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.90

K781-1482 in Drug Discovery

Included in Screening Libraries

MCL1 Targeted Library (12200 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic

References: we are preparing a list of scientific research reports with K781-1482 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K781-1482?
Check Price and Availability of K781-1482, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K781-1482 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K781-1482
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K781-1482
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K781-1482 available by request