K783-2921 Screening compound: 5,5,11-trioxo-10,11-dihydro-5H-5lambda~6~-dibenzo[b,f][1,4]thiazepine-8-carboxylic acid

K783-2921 Screening compound: 5,5,11-trioxo-10,11-dihydro-5H-5lambda~6~-dibenzo[b,f][1,4]thiazepine-8-carboxylic acid
K783-2921 Screening compound: 5,5,11-trioxo-10,11-dihydro-5H-5lambda~6~-dibenzo[b,f][1,4]thiazepine-8-carboxylic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound K783-2921
5,5,11-trioxo-10,11-dihydro-5H-5lambda~6~-dibenzo[b,f][1,4]thiazepine-8-carboxylic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K783-2921

Molecular Formula

C14H9NO5S (C14 H9 NO5 S)

Compound Name

5,5,11-trioxo-10,11-dihydro-5H-5lambda~6~-dibenzo[b,f][1,4]thiazepine-8-carboxylic acid

IUPAC name

2210-trioxo-2lambda6-thia-9-azatricyclo[9.4.0.0^{38}]pentadeca-1(11)3(8)461214-hexaene-6-carboxylic acid

SMILES

OC(c(cc1)cc(NC(c2c3cccc2)=O)c1S3(=O)=O)=O

InChI

InChI=1S/C14H9NO5S/c16-13-9-3-1-2-4-11(9)21(19,20)12-6-5-8(14(17)18)7-10(12)15-13/h1-7H,(H,15,16)(H,17,18)

InChI Key

UEKIEJNYSPXCAW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03450383

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

303.3

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.984

Distribution Coefficient, logD

-0.570

Water Solubility, LogSw

-2.76

Polar Surface Area

82.564

Acid Dissociation Constant (pKa)

4.85

Base Dissociation Constant (pKb)

-8.42

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

K783-2921 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anti-Aging Library (44940 compounds)

Antiviral Library (67538 compounds)

Protein-Protein Interaction Library (218420 compounds)

Soluble Diversity Library (15920 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Epigenetic
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with K783-2921 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K783-2921?
Check Price and Availability of K783-2921, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K783-2921 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K783-2921
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K783-2921
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K783-2921 available by request