K783-4358 Screening compound: 5-(thiophen-2-yl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-2-thiol

K783-4358 Screening compound: 5-(thiophen-2-yl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-2-thiol
K783-4358 Screening compound: 5-(thiophen-2-yl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-2-thiol alternative view

Chemical Structure Depiction of ChemDiv screening compound K783-4358
5-(thiophen-2-yl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-2-thiol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K783-4358

Molecular Formula

C10H5F3N4S2 (C10 H5 F3 N4 S2)

Compound Name

5-(thiophen-2-yl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-2-thiol

IUPAC name

5-(thiophen-2-yl)-7-(trifluoromethyl)-[124]triazolo[15-a]pyrimidine-2-thiol

SMILES

FC(c1cc(-c2cccs2)nc2nc(S)nn12)(F)F

InChI

InChI=1S/C10H5F3N4S2/c11-10(12,13)7-4-5(6-2-1-3-19-6)14-8-15-9(18)16-17(7)8/h1-4H,(H,16,18)

InChI Key

MWSNGQDSEZVGRF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03450628

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

302.3

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.072

Distribution Coefficient, logD

3.059

Water Solubility, LogSw

-3.09

Polar Surface Area

28.398

Acid Dissociation Constant (pKa)

8.95

Base Dissociation Constant (pKb)

1.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

K783-4358 in Drug Discovery

Included in Screening Libraries

Carbonic Anhydrase II Library (4939 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Agro:
  • Agro

References: we are preparing a list of scientific research reports with K783-4358 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K783-4358?
Check Price and Availability of K783-4358, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K783-4358 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K783-4358
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K783-4358
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K783-4358 available by request