K783-5603 Screening compound: 3-[3-(diethylamino)propyl]-1-(2,4-dimethylphenyl)-3-[(1H-indol-3-yl)methyl]thiourea

K783-5603 Screening compound: 3-[3-(diethylamino)propyl]-1-(2,4-dimethylphenyl)-3-[(1H-indol-3-yl)methyl]thiourea
K783-5603 Screening compound: 3-[3-(diethylamino)propyl]-1-(2,4-dimethylphenyl)-3-[(1H-indol-3-yl)methyl]thiourea alternative view

Chemical Structure Depiction of ChemDiv screening compound K783-5603
3-[3-(diethylamino)propyl]-1-(2,4-dimethylphenyl)-3-[(1H-indol-3-yl)methyl]thiourea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K783-5603

Molecular Formula

C25H34N4S (C25 H34 N4 S)

Compound Name

3-[3-(diethylamino)propyl]-1-(2,4-dimethylphenyl)-3-[(1H-indol-3-yl)methyl]thiourea

IUPAC name

3-[3-(diethylamino)propyl]-1-(24-dimethylphenyl)-3-[(1H-indol-3-yl)methyl]thiourea

SMILES

CCN(CC)CCCN(Cc1c[nH]c2c1cccc2)C(Nc1c(C)cc(C)cc1)=S

InChI

InChI=1S/C25H34N4S/c1-5-28(6-2)14-9-15-29(18-21-17-26-24-11-8-7-10-22(21)24)25(30)27-23-13-12-19(3)16-20(23)4/h7-8,10-13,16-17,26H,5-6,9,14-15,18H2,1-4H3,(H,27,30)

InChI Key

FCUUDVCZKMRKLO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27225447

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

422.64

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.899

Distribution Coefficient, logD

3.713

Water Solubility, LogSw

-5.68

Polar Surface Area

23.262

Acid Dissociation Constant (pKa)

14.94

Base Dissociation Constant (pKb)

9.58

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

K783-5603 in Drug Discovery

Included in Screening Libraries

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with K783-5603 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K783-5603?
Check Price and Availability of K783-5603, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K783-5603 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K783-5603
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K783-5603
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K783-5603 available by request