K783-5960 Screening compound: 2-[(2E)-3-(5-bromo-2-methoxyphenyl)prop-2-enamido]acetic acid

K783-5960 Screening compound: 2-[(2E)-3-(5-bromo-2-methoxyphenyl)prop-2-enamido]acetic acid
K783-5960 Screening compound: 2-[(2E)-3-(5-bromo-2-methoxyphenyl)prop-2-enamido]acetic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound K783-5960
2-[(2E)-3-(5-bromo-2-methoxyphenyl)prop-2-enamido]acetic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K783-5960

Molecular Formula

C12H12BrNO4 (C12 H12 BrNO4)

Compound Name

2-[(2E)-3-(5-bromo-2-methoxyphenyl)prop-2-enamido]acetic acid

IUPAC name

2-[(2E)-3-(5-bromo-2-methoxyphenyl)prop-2-enamido]acetic acid

SMILES

COc(cc1)c(/C=C/C(NCC(O)=O)=O)cc1Br

InChI

InChI=1S/C12H12BrNO4/c1-18-10-4-3-9(13)6-8(10)2-5-11(15)14-7-12(16)17/h2-6H,7H2,1H3,(H,14,15)(H,16,17)

InChI Key

SSUTVDFFMWGYMS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11548333

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

314.14

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.582

Distribution Coefficient, logD

-2.053

Water Solubility, LogSw

-1.91

Polar Surface Area

60.724

Acid Dissociation Constant (pKa)

3.76

Base Dissociation Constant (pKb)

0.40

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

K783-5960 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

RAR (Nuclear receptors) Ligands Library (6524 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Respiratory tract
  • Eye
  • Male
  • Female
  • Hemic and lymphatic
  • Congenital
  • Skin
  • Endocrine
  • Immune system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Kinases
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with K783-5960 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K783-5960?
Check Price and Availability of K783-5960, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K783-5960 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K783-5960
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K783-5960
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K783-5960 available by request