K784-2037 Screening compound: 11-chlorodibenzo[b,f][1,4]thiazepine-8-carboxylic acid

K784-2037 Screening compound: 11-chlorodibenzo[b,f][1,4]thiazepine-8-carboxylic acid
K784-2037 Screening compound: 11-chlorodibenzo[b,f][1,4]thiazepine-8-carboxylic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound K784-2037
11-chlorodibenzo[b,f][1,4]thiazepine-8-carboxylic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K784-2037

Molecular Formula

C14H8ClNO2S (C14 H8 ClNO2 S)

Compound Name

11-chlorodibenzo[b,f][1,4]thiazepine-8-carboxylic acid

IUPAC name

10-chloro-2-thia-9-azatricyclo[9.4.0.0^{38}]pentadeca-1(15)3(8)4691113-heptaene-6-carboxylic acid

SMILES

OC(c(cc1)cc2c1Sc(cccc1)c1C(Cl)=N2)=O

InChI

InChI=1S/C14H8ClNO2S/c15-13-9-3-1-2-4-11(9)19-12-6-5-8(14(17)18)7-10(12)16-13/h1-7H,(H,17,18)

InChI Key

XNWFMIKUWGVBLZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03450663

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

289.74

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

4.191

Distribution Coefficient, logD

0.998

Water Solubility, LogSw

-4.41

Polar Surface Area

37.409

Acid Dissociation Constant (pKa)

4.21

Base Dissociation Constant (pKb)

2.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

K784-2037 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

NOTUM (Wnt signaling) Library (3881 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K784-2037 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K784-2037?
Check Price and Availability of K784-2037, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K784-2037 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K784-2037
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K784-2037
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K784-2037 available by request