K784-4265 Screening compound: 3-cyclohexyl-3-[(2-fluorophenyl)methyl]-1-(4-phenoxyphenyl)thiourea

K784-4265 Screening compound: 3-cyclohexyl-3-[(2-fluorophenyl)methyl]-1-(4-phenoxyphenyl)thiourea
K784-4265 Screening compound: 3-cyclohexyl-3-[(2-fluorophenyl)methyl]-1-(4-phenoxyphenyl)thiourea alternative view

Chemical Structure Depiction of ChemDiv screening compound K784-4265
3-cyclohexyl-3-[(2-fluorophenyl)methyl]-1-(4-phenoxyphenyl)thiourea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K784-4265

Molecular Formula

C26H27FN2OS (C26 H27 FN2 OS)

Compound Name

3-cyclohexyl-3-[(2-fluorophenyl)methyl]-1-(4-phenoxyphenyl)thiourea

IUPAC name

3-cyclohexyl-3-[(2-fluorophenyl)methyl]-1-(4-phenoxyphenyl)thiourea

SMILES

Fc1c(CN(C2CCCCC2)C(Nc(cc2)ccc2Oc2ccccc2)=S)cccc1

InChI

InChI=1S/C26H27FN2OS/c27-25-14-8-7-9-20(25)19-29(22-10-3-1-4-11-22)26(31)28-21-15-17-24(18-16-21)30-23-12-5-2-6-13-23/h2,5-9,12-18,22H,1,3-4,10-11,19H2,(H,28,31)

InChI Key

ONFARFSLFFWALK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03450985

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434.58

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

7.692

Distribution Coefficient, logD

7.692

Water Solubility, LogSw

-6.12

Polar Surface Area

16.420

Acid Dissociation Constant (pKa)

15.77

Base Dissociation Constant (pKb)

0.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.90

K784-4265 in Drug Discovery

Included in Screening Libraries

MCL1 Targeted Library (12200 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with K784-4265 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K784-4265?
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What is the minimum amount of K784-4265 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K784-4265
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K784-4265
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K784-4265 available by request