K784-8244 Screening compound: 6-[(2-chloro-6-fluorophenyl)methyl]-N-[3-(diethylamino)propyl]-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide

K784-8244 Screening compound: 6-[(2-chloro-6-fluorophenyl)methyl]-N-[3-(diethylamino)propyl]-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide
K784-8244 Screening compound: 6-[(2-chloro-6-fluorophenyl)methyl]-N-[3-(diethylamino)propyl]-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K784-8244
6-[(2-chloro-6-fluorophenyl)methyl]-N-[3-(diethylamino)propyl]-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K784-8244

Molecular Formula

C23H29ClFN5O (C23 H29 ClFN5 O)

Compound Name

6-[(2-chloro-6-fluorophenyl)methyl]-N-[3-(diethylamino)propyl]-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide

IUPAC name

6-[(2-chloro-6-fluorophenyl)methyl]-N-[3-(diethylamino)propyl]-57-dimethylpyrazolo[15-a]pyrimidine-3-carboxamide

SMILES

CCN(CC)CCCNC(c1c2nc(C)c(Cc(c(F)ccc3)c3Cl)c(C)n2nc1)=O

InChI

InChI=1S/C23H29ClFN5O/c1-5-29(6-2)12-8-11-26-23(31)19-14-27-30-16(4)17(15(3)28-22(19)30)13-18-20(24)9-7-10-21(18)25/h7,9-10,14H,5-6,8,11-13H2,1-4H3,(H,26,31)

InChI Key

KXMRJVILYWEWJM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15099165

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.97

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.058

Distribution Coefficient, logD

1.337

Water Solubility, LogSw

-4.47

Polar Surface Area

48.429

Acid Dissociation Constant (pKa)

14.62

Base Dissociation Constant (pKb)

10.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

43.50

K784-8244 in Drug Discovery

Included in Screening Libraries

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with K784-8244 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K784-8244?
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What is the minimum amount of K784-8244 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K784-8244
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K784-8244
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K784-8244 available by request