K786-0389 Screening compound: 4-(2,3-dihydro-1H-indol-1-yl)-N-[3-(dipropylamino)propyl]-3-(1H-imidazol-1-yl)-4-oxobutanamide

K786-0389 Screening compound: 4-(2,3-dihydro-1H-indol-1-yl)-N-[3-(dipropylamino)propyl]-3-(1H-imidazol-1-yl)-4-oxobutanamide
K786-0389 Screening compound: 4-(2,3-dihydro-1H-indol-1-yl)-N-[3-(dipropylamino)propyl]-3-(1H-imidazol-1-yl)-4-oxobutanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K786-0389
4-(2,3-dihydro-1H-indol-1-yl)-N-[3-(dipropylamino)propyl]-3-(1H-imidazol-1-yl)-4-oxobutanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K786-0389

Molecular Formula

C24H35N5O2 (C24 H35 N5 O2)

Compound Name

4-(2,3-dihydro-1H-indol-1-yl)-N-[3-(dipropylamino)propyl]-3-(1H-imidazol-1-yl)-4-oxobutanamide

IUPAC name

4-(23-dihydro-1H-indol-1-yl)-N-[3-(dipropylamino)propyl]-3-(1H-imidazol-1-yl)-4-oxobutanamide

SMILES

CCCN(CCC)CCCNC(CC(C(N(CC1)c2c1cccc2)=O)n1cncc1)=O

InChI

InChI=1S/C24H35N5O2/c1-3-13-27(14-4-2)15-7-11-26-23(30)18-22(28-17-12-25-19-28)24(31)29-16-10-20-8-5-6-9-21(20)29/h5-6,8-9,12,17,19,22H,3-4,7,10-11,13-16,18H2,1-2H3,(H,26,30)/t22-/m0/s1

InChI Key

KUOXNWOMODGYTN-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD03830869

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

425.57

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

14.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.700

Distribution Coefficient, logD

-1.116

Water Solubility, LogSw

-1.96

Polar Surface Area

56.683

Acid Dissociation Constant (pKa)

15.05

Base Dissociation Constant (pKb)

10.22

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

54.20

K786-0389 in Drug Discovery

Included in Screening Libraries

Dark Chemical Matter Library (18430 compounds)

Eccentric PPI Library (11937 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Anti-HIV1 Library (19540 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Structure:
  • Pool
  • Cyclic compounds
  • Mimetics
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with K786-0389 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K786-0389?
Check Price and Availability of K786-0389, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K786-0389 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K786-0389
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K786-0389
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K786-0389 available by request