K786-1761 Screening compound: 3-(3,4-dichlorophenyl)-1-[(3-methylphenyl)methyl]-1-(pyridin-2-yl)urea

K786-1761 Screening compound: 3-(3,4-dichlorophenyl)-1-[(3-methylphenyl)methyl]-1-(pyridin-2-yl)urea
K786-1761 Screening compound: 3-(3,4-dichlorophenyl)-1-[(3-methylphenyl)methyl]-1-(pyridin-2-yl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound K786-1761
3-(3,4-dichlorophenyl)-1-[(3-methylphenyl)methyl]-1-(pyridin-2-yl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K786-1761

Molecular Formula

C20H17Cl2N3O (C20 H17 Cl2 N3 O)

Compound Name

3-(3,4-dichlorophenyl)-1-[(3-methylphenyl)methyl]-1-(pyridin-2-yl)urea

IUPAC name

3-(34-dichlorophenyl)-1-[(3-methylphenyl)methyl]-1-(pyridin-2-yl)urea

SMILES

Cc1cccc(CN(C(Nc(cc2)cc(Cl)c2Cl)=O)c2ncccc2)c1

InChI

InChI=1S/C20H17Cl2N3O/c1-14-5-4-6-15(11-14)13-25(19-7-2-3-10-23-19)20(26)24-16-8-9-17(21)18(22)12-16/h2-12H,13H2,1H3,(H,24,26)

InChI Key

JFXYXRVAPVJCOI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03831142

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

386.28

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.594

Distribution Coefficient, logD

6.593

Water Solubility, LogSw

-6.20

Polar Surface Area

32.922

Acid Dissociation Constant (pKa)

10.15

Base Dissociation Constant (pKb)

4.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

K786-1761 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Nervous system
  • Nervous system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with K786-1761 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K786-1761?
Check Price and Availability of K786-1761, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K786-1761 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K786-1761
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K786-1761
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K786-1761 available by request