K786-3117 Screening compound: N-[(2-chlorophenyl)methyl]-6-(morpholine-4-sulfonyl)-2-(pyridin-2-yl)quinoline-4-carboxamide

K786-3117 Screening compound: N-[(2-chlorophenyl)methyl]-6-(morpholine-4-sulfonyl)-2-(pyridin-2-yl)quinoline-4-carboxamide
K786-3117 Screening compound: N-[(2-chlorophenyl)methyl]-6-(morpholine-4-sulfonyl)-2-(pyridin-2-yl)quinoline-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K786-3117
N-[(2-chlorophenyl)methyl]-6-(morpholine-4-sulfonyl)-2-(pyridin-2-yl)quinoline-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K786-3117

Molecular Formula

C26H23ClN4O4S (C26 H23 ClN4 O4 S)

Compound Name

N-[(2-chlorophenyl)methyl]-6-(morpholine-4-sulfonyl)-2-(pyridin-2-yl)quinoline-4-carboxamide

IUPAC name

N-[(2-chlorophenyl)methyl]-6-(morpholine-4-sulfonyl)-2-(pyridin-2-yl)quinoline-4-carboxamide

SMILES

O=C(c(c1c2)cc(-c3ncccc3)nc1ccc2S(N1CCOCC1)(=O)=O)NCc(cccc1)c1Cl

InChI

InChI=1S/C26H23ClN4O4S/c27-22-6-2-1-5-18(22)17-29-26(32)21-16-25(24-7-3-4-10-28-24)30-23-9-8-19(15-20(21)23)36(33,34)31-11-13-35-14-12-31/h1-10,15-16H,11-14,17H2,(H,29,32)

InChI Key

ZRFVSSYYDPIOTP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15100730

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

523.01

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.404

Distribution Coefficient, logD

4.404

Water Solubility, LogSw

-4.49

Polar Surface Area

81.378

Acid Dissociation Constant (pKa)

13.30

Base Dissociation Constant (pKb)

3.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.20

K786-3117 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

Purinergic Library (3321 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Cardiovascular
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Ion Channels
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K786-3117 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K786-3117?
Check Price and Availability of K786-3117, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K786-3117 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K786-3117
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K786-3117
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K786-3117 available by request