K786-3665 Screening compound: 3'-benzoyl-4'-(3-chlorophenyl)-1-[(3-chlorophenyl)methyl]-1'-methyl-1,2-dihydrospiro[indole-3,2'-pyrrolidin]-2-one

K786-3665 Screening compound: 3'-benzoyl-4'-(3-chlorophenyl)-1-[(3-chlorophenyl)methyl]-1'-methyl-1,2-dihydrospiro[indole-3,2'-pyrrolidin]-2-one
K786-3665 Screening compound: 3'-benzoyl-4'-(3-chlorophenyl)-1-[(3-chlorophenyl)methyl]-1'-methyl-1,2-dihydrospiro[indole-3,2'-pyrrolidin]-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K786-3665
3'-benzoyl-4'-(3-chlorophenyl)-1-[(3-chlorophenyl)methyl]-1'-methyl-1,2-dihydrospiro[indole-3,2'-pyrrolidin]-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K786-3665

Molecular Formula

C32H26Cl2N2O2 (C32 H26 Cl2 N2 O2)

Compound Name

3'-benzoyl-4'-(3-chlorophenyl)-1-[(3-chlorophenyl)methyl]-1'-methyl-1,2-dihydrospiro[indole-3,2'-pyrrolidin]-2-one

IUPAC name

3'-benzoyl-4'-(3-chlorophenyl)-1-[(3-chlorophenyl)methyl]-1'-methyl-12-dihydrospiro[indole-32'-pyrrolidin]-2-one

SMILES

CN(CC(C1C(c2ccccc2)=O)c2cccc(Cl)c2)C1(c(cccc1)c1N1Cc2cc(Cl)ccc2)C1=O

InChI

InChI=1S/C32H26Cl2N2O2/c1-35-20-26(23-12-8-14-25(34)18-23)29(30(37)22-10-3-2-4-11-22)32(35)27-15-5-6-16-28(27)36(31(32)38)19-21-9-7-13-24(33)17-21/h2-18,26,29H,19-20H2,1H3

InChI Key

YJCVWDATHLBBNV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15100892

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

541.48

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

7.292

Distribution Coefficient, logD

7.292

Water Solubility, LogSw

-6.23

Polar Surface Area

31.767

Acid Dissociation Constant (pKa)

16.63

Base Dissociation Constant (pKb)

1.18

Number of Chiral Centers

3.00

Percent sp3 carbon bonding

18.80

K786-3665 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Nervous system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • GPCR
  • Ion Channels
  • Proteases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with K786-3665 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K786-3665?
Check Price and Availability of K786-3665, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K786-3665 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K786-3665
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K786-3665
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K786-3665 available by request