K786-3674 Screening compound: 1-(3,4-dichlorophenyl)-3-[5-(morpholine-4-carbonyl)-2-(piperidin-1-yl)phenyl]urea

K786-3674 Screening compound: 1-(3,4-dichlorophenyl)-3-[5-(morpholine-4-carbonyl)-2-(piperidin-1-yl)phenyl]urea
K786-3674 Screening compound: 1-(3,4-dichlorophenyl)-3-[5-(morpholine-4-carbonyl)-2-(piperidin-1-yl)phenyl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound K786-3674
1-(3,4-dichlorophenyl)-3-[5-(morpholine-4-carbonyl)-2-(piperidin-1-yl)phenyl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K786-3674

Molecular Formula

C23H26Cl2N4O3 (C23 H26 Cl2 N4 O3)

Compound Name

1-(3,4-dichlorophenyl)-3-[5-(morpholine-4-carbonyl)-2-(piperidin-1-yl)phenyl]urea

IUPAC name

1-(34-dichlorophenyl)-3-[5-(morpholine-4-carbonyl)-2-(piperidin-1-yl)phenyl]urea

SMILES

O=C(c(cc1)cc(NC(Nc(cc2)cc(Cl)c2Cl)=O)c1N1CCCCC1)N1CCOCC1

InChI

InChI=1S/C23H26Cl2N4O3/c24-18-6-5-17(15-19(18)25)26-23(31)27-20-14-16(22(30)29-10-12-32-13-11-29)4-7-21(20)28-8-2-1-3-9-28/h4-7,14-15H,1-3,8-13H2,(H2,26,27,31)

InChI Key

NGXROELOJQRUIC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15100899

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

477.39

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.993

Distribution Coefficient, logD

4.992

Water Solubility, LogSw

-5.24

Polar Surface Area

59.552

Acid Dissociation Constant (pKa)

10.18

Base Dissociation Constant (pKb)

4.26

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

K786-3674 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

Lipid Metabolism Library (9174 compounds)

Regenerative Medicine Focused Library (23016 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Nervous system
  • Cardiovascular
  • Metabolic
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Targets:
  • Others

References: we are preparing a list of scientific research reports with K786-3674 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K786-3674?
Check Price and Availability of K786-3674, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K786-3674 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K786-3674
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K786-3674
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K786-3674 available by request