K786-6470 Screening compound: N-(4-CHLOROPHENETHYL)-1-(1,4-DIOXA-8-AZASPIRO[4.5]DEC-8-YLSULFONYL)-4-PIPERIDINECARBOXAMIDE

K786-6470 Screening compound: N-(4-CHLOROPHENETHYL)-1-(1,4-DIOXA-8-AZASPIRO[4.5]DEC-8-YLSULFONYL)-4-PIPERIDINECARBOXAMIDE
K786-6470 Screening compound: N-(4-CHLOROPHENETHYL)-1-(1,4-DIOXA-8-AZASPIRO[4.5]DEC-8-YLSULFONYL)-4-PIPERIDINECARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound K786-6470
N-(4-CHLOROPHENETHYL)-1-(1,4-DIOXA-8-AZASPIRO[4.5]DEC-8-YLSULFONYL)-4-PIPERIDINECARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K786-6470

Molecular Formula

C21H30ClN3O5S (C21 H30 ClN3 O5 S)

Compound Name

N-(4-CHLOROPHENETHYL)-1-(1,4-DIOXA-8-AZASPIRO[4.5]DEC-8-YLSULFONYL)-4-PIPERIDINECARBOXAMIDE

IUPAC name

N-[2-(4-chlorophenyl)ethyl]-1-{14-dioxa-8-azaspiro[4.5]decane-8-sulfonyl}piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1S(N(CC1)CCC11OCCO1)(=O)=O)NCCc(cc1)ccc1Cl

InChI

InChI=1S/C21H30ClN3O5S/c22-19-3-1-17(2-4-19)5-10-23-20(26)18-6-11-24(12-7-18)31(27,28)25-13-8-21(9-14-25)29-15-16-30-21/h1-4,18H,5-16H2,(H,23,26)

InChI Key

MBEWINRDLZINTB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15101448

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.01

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.619

Distribution Coefficient, logD

1.619

Water Solubility, LogSw

-2.86

Polar Surface Area

73.047

Acid Dissociation Constant (pKa)

13.94

Base Dissociation Constant (pKb)

4.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

66.67

K786-6470 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

GPCR Targeted Library (31838 compounds)

Human GPCR Annotated Library (5539 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • GPCR
  • Proteases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K786-6470 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K786-6470?
Check Price and Availability of K786-6470, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K786-6470 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K786-6470
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K786-6470
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K786-6470 available by request