K786-7473 Screening compound: 8-{2-[(2,4-difluorophenyl)sulfanyl]quinoline-4-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane

K786-7473 Screening compound: 8-{2-[(2,4-difluorophenyl)sulfanyl]quinoline-4-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane
K786-7473 Screening compound: 8-{2-[(2,4-difluorophenyl)sulfanyl]quinoline-4-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound K786-7473
8-{2-[(2,4-difluorophenyl)sulfanyl]quinoline-4-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K786-7473

Molecular Formula

C23H20F2N2O3S (C23 H20 F2 N2 O3 S)

Compound Name

8-{2-[(2,4-difluorophenyl)sulfanyl]quinoline-4-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane

IUPAC name

8-{2-[(24-difluorophenyl)sulfanyl]quinoline-4-carbonyl}-14-dioxa-8-azaspiro[4.5]decane

SMILES

O=C(c1cc(Sc(ccc(F)c2)c2F)nc2ccccc12)N(CC1)CCC11OCCO1

InChI

InChI=1S/C23H20F2N2O3S/c24-15-5-6-20(18(25)13-15)31-21-14-17(16-3-1-2-4-19(16)26-21)22(28)27-9-7-23(8-10-27)29-11-12-30-23/h1-6,13-14H,7-12H2

InChI Key

FJOOZOZQMNCTBD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05030536

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

442.49

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.225

Distribution Coefficient, logD

4.225

Water Solubility, LogSw

-4.24

Polar Surface Area

38.744

Acid Dissociation Constant (pKa)

27.30

Base Dissociation Constant (pKb)

6.92

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

K786-7473 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Antiviral
  • Infections
  • Immune system
Agro:
  • Agro

References: we are preparing a list of scientific research reports with K786-7473 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K786-7473?
Check Price and Availability of K786-7473, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K786-7473 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K786-7473
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K786-7473
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K786-7473 available by request