K786-7492 Screening compound: 2-[(2,4-difluorophenyl)sulfanyl]-N~4~-(2-morpholinoethyl)-4-quinolinecarboxamide

K786-7492 Screening compound: 2-[(2,4-difluorophenyl)sulfanyl]-N~4~-(2-morpholinoethyl)-4-quinolinecarboxamide
K786-7492 Screening compound: 2-[(2,4-difluorophenyl)sulfanyl]-N~4~-(2-morpholinoethyl)-4-quinolinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K786-7492
2-[(2,4-difluorophenyl)sulfanyl]-N~4~-(2-morpholinoethyl)-4-quinolinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K786-7492

Molecular Formula

C22H21F2N3O2S (C22 H21 F2 N3 O2 S)

Compound Name

2-[(2,4-difluorophenyl)sulfanyl]-N~4~-(2-morpholinoethyl)-4-quinolinecarboxamide

IUPAC name

n/a

SMILES

O=C(c1cc(Sc(ccc(F)c2)c2F)nc2ccccc12)NCCN1CCOCC1

InChI

InChI=1S/C22H21F2N3O2S/c23-15-5-6-20(18(24)13-15)30-21-14-17(16-3-1-2-4-19(16)26-21)22(28)25-7-8-27-9-11-29-12-10-27/h1-6,13-14H,7-12H2,(H,25,28)

InChI Key

URBFYCQLNYAYLF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15101745

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

429.49

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.972

Distribution Coefficient, logD

3.958

Water Solubility, LogSw

-4.11

Polar Surface Area

43.805

Acid Dissociation Constant (pKa)

14.15

Base Dissociation Constant (pKb)

5.92

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

K786-7492 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

C-Met Library (15277 compounds)

Dark Chemical Matter Library (18430 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands
Structure:
  • Pool

References: we are preparing a list of scientific research reports with K786-7492 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K786-7492?
Check Price and Availability of K786-7492, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K786-7492 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K786-7492
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K786-7492
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K786-7492 available by request