K788-1488 Screening compound: 10-(2-chlorobenzyl)-8-(morpholinocarbonyl)dibenzo[b,f][1,4]thiazepin-11(10H)-one

K788-1488 Screening compound: 10-(2-chlorobenzyl)-8-(morpholinocarbonyl)dibenzo[b,f][1,4]thiazepin-11(10H)-one
K788-1488 Screening compound: 10-(2-chlorobenzyl)-8-(morpholinocarbonyl)dibenzo[b,f][1,4]thiazepin-11(10H)-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K788-1488
10-(2-chlorobenzyl)-8-(morpholinocarbonyl)dibenzo[b,f][1,4]thiazepin-11(10H)-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K788-1488

Molecular Formula

C25H21ClN2O3S (C25 H21 ClN2 O3 S)

Compound Name

10-(2-chlorobenzyl)-8-(morpholinocarbonyl)dibenzo[b,f][1,4]thiazepin-11(10H)-one

IUPAC name

9-[(2-chlorophenyl)methyl]-6-(morpholine-4-carbonyl)-2-thia-9-azatricyclo[9.4.0.0^{38}]pentadeca-1(11)3571214-hexaen-10-one

SMILES

O=C(c(cc1)cc(N2Cc(cccc3)c3Cl)c1Sc(cccc1)c1C2=O)N1CCOCC1

InChI

InChI=1S/C25H21ClN2O3S/c26-20-7-3-1-5-18(20)16-28-21-15-17(24(29)27-11-13-31-14-12-27)9-10-23(21)32-22-8-4-2-6-19(22)25(28)30/h1-10,15H,11-14,16H2

InChI Key

GFUBHSLVEXMAHZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15103164

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

464.97

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.501

Distribution Coefficient, logD

4.501

Water Solubility, LogSw

-4.58

Polar Surface Area

39.957

Acid Dissociation Constant (pKa)

26.76

Base Dissociation Constant (pKb)

-4.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

K788-1488 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with K788-1488 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K788-1488?
Check Price and Availability of K788-1488, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K788-1488 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K788-1488
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K788-1488
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K788-1488 available by request